I got this error in the Application Event log every time a user wanted to open a pdf file from the Internet Explorer on several brand new Windows Server 2008 RDS hosts. Acrobat tries to open a pdf file in the Internet browser but crashes. I’ve solved this by disabling the browser integration in Acrobat Reader by running the following command from the login script:
REG ADD “HKEY_CURRENT_USER\Software\Adobe\Acrobat Reader\9.0\Originals” /v “bBrowserIntegration” /t REG_DWORD /d 0 /f
Now, when a user logs in on a RDS host and opens a pdf file from the Internet Explorer, the file is first downloaded to a temporary folder and opened from there. The pdf file will no longer be opened within the Internet Explorer.